Collaborators
Clinical Ophthalmology
Dr Amanda Greaves (Terrace Eye Centre, Brisbane)
Dr Albert Aralar (Terrace Eye Centre, Brisbane)
Dr Philip Windle (Terrace Eye Centre, Brisbane)
Dr Anthony Kwan (Queensland Eye Institute)
Basic Ophthalmology
Adjunct Prof Brian Brown (Vision Improvement Domain, IHBI, QUT)
Dr Damien Harkin (Vision Improvement Domain, IHBI, QUT)
Dr Andrew Zele (Vision Improvement Domain, IHBI, QUT)
Dr Ian Stewart (Injury Prevention and Rehabilitation Domain, IHBI, QUT)
International Collaboration
Dr Anton Haas, Clinical Professor of Ophthalmology (University Department of Ophthalmology, Graz, Austria)
Prof Jan Kremers (University Hospital Erlangen Department of Ophthalmology, Germany)
Dr Dingcai Cao (University of Chicago, Department of Ophthalmology and Vision Science, USA)
The research program of the Medical Retina Laboratory is centred on understanding neuroretinal and anatomical function in the human eye. Its focus is to consider the effects of reduced oxygenation (hypoxia) on neuroretinal function in humans using in vivo and in vitro methods. The work is directly linked to the laboratory's clinical investigations that concentrate on ageing and retinal disease, specifically, age-related maculopathy (ARM). Clinical investigations consider methods for early detection, monitoring and treatment strategies of retinal eye disease. The in vivo research techniques include multifocal and focal electroretinography in combination with an 8-channel photostimulator and optical coherence tomography. The in vitro studies investigate normoxia and hypoxia using cultured human retinal pigment epithelial cells.
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Current Research Programs
- Hypoxia and neuroretinal function (Feigl et al, Clin Neurophysiology 2007; 118: 887-895)
- Retinal pigment epithelium cell responses to hypoxia and growth factors (VEGF, IGF-1)
- Independent control of local electrical response of the human retinal photoreceptors
- Understanding the pathogenesis of ARM (Feigl et al, Eye 2007; 21: 689-96)
- Understanding of new treatments in ARM (Feigl et al Clin Ophthalmology 2007; 1: 1-9)